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      <title>A pipeline approach for discovery of novel CRISRP-Cas systems</title>
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      <title>C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector</title>
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      <title>Discovery and functional characterization of diverse class 2 CRISPR-Cas systems</title>
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      <title>MD 20894, USA 3 Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA, McGovern Institute for Brain Research, Department of Brain and Cognitive Science, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts</title>
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      <title>Pervasive generation of oppositely oriented spacers during CRISPR adaptation</title>
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