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      <title>Dynamics of Escherichia coli type I-E CRISPR spacers over 42 000 years</title>
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      <title>A pipeline approach for discovery of novel CRISRP-Cas systems</title>
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      <title>Metagenomic analysis of bacterial communities of Antarctic surface snow</title>
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      <title>Discovery and functional characterization of diverse class 2 CRISPR-Cas systems</title>
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      <title>MD 20894, USA 3 Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA, McGovern Institute for Brain Research, Department of Brain and Cognitive Science, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts</title>
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      <title>Pervasive generation of oppositely oriented spacers during CRISPR adaptation</title>
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